San Gerónimo Tlamaco is a locality in Mexico belonging to the municipality of Atitalaquia in the state of Hidalgo.

During the territorial expansion of the Triple Alliance, Moctezuma Ilhuicamina conquered the region of Teotlalpan, north of the Mexica Empire.

Years later, the viceroy Martín Enríquez de Almansa ordered that the indigenous people join their houses to form towns.

[6] The Franciscan order was in charge of carrying out the work of evangelization in Tlamaco, consisting of teaching the indigenous people the Spanish language, Catholic doctrine and new forms of cultivation.

In the 1570s, the friars were in charge of leading the inhabitants of Tlamaco in the construction of a chapel in honor of San Jerónimo using the area's pink quarry as raw material.