San Marcellino is a comune (municipality) in the Province of Caserta in the Italian region Campania, located about 20 kilometres (12 mi) northwest of Naples and about 15 kilometres (9 mi) southwest of Caserta.

San Marcellino borders the following municipalities: Aversa, Casapesenna, Frignano, Trentola-Ducenta, Villa di Briano.

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