After Masaniello's revolution of 1647, the pharmacist Sabato Anella took pity on the many children orphaned in the upheavals, and created an orphanage at his home near Sedile di Porto.
Thereafter the Count of Oñate, then Viceroy, obtained a building at this site from the Marquis of Mari.
A church and adjacent oratory-church were built, and supervised by a monastic order.
Over time, the house was transformed into a monastery open to youngsters from wealthy families.
The church has a central Greek cross plan with a circular room, decorated in baroque style with Corinthian columns.