The title was previously raised pro hac vice after José Tomás Sánchez was installed cardinal-priest in 2002, ten years after serving as cardinal-deacon.

The nave door is inset, and above it is a mosaic by Giuseppe Stracota depicting Pope Pius V and St George with the Madonna and Child, and a background showing the Battle of Lepanto (at which the navy of the Ottoman Turks was defeated during his pontificate).

The first story of the façade, and the body of the nave above the aisles, is divided into panels by relief pilasters in brick without capitals.

In the centre is a vertical rectangular window formed of six squares divided by stone mullions, and below this are a coat of arms.

There are some notable devotional artworks: the crucifix is by Francisco Nagni, the Stations of the Cross by Angelo Biancini, the statue of St Catherine of Siena by Antonio Berti and an angel in gesso by Duilio Cambellotti.