[4][5] San Vito lies on the Via Aemilia,[6] an ancient Roman road between Ariminum (modern Rimini) and Placentia (Piacenza) that dates to Marcus Aemilius Lepidus in 187 BC.

[7] The section of the Via Aemilia between Savignano sul Rubicone and Santa Giustina, now known as the Via Emilia Vecchia,[6] replaced an earlier routing of the road through Santarcangelo di Romagna.

[8][9] San Vito is on the right bank of the river Uso [it],[1][2] which flows from Perticara [it], a frazione of Novafeltria, to the Adriatic Sea in Bellaria–Igea Marina.

Its new parish priest, Don Giovanni Marconi, founded San Vito's Cassa Rurale di Depositi e Prestiti on 25 March 1914.

[4][17] The stones of the bridges, prized for their excellent quality, were quarried over subsequent centuries,[4][8] contributing also to restorations of Rimini's Ponte di Tiberio.

[4][5] On the Via Aemilia between San Vito and Santa Giustina is a seventeenth-century Marian shrine, the Sanctuary of Madonna di Casale, locally renowned for its Virgin and Child fresco.

In June 1596, the first miracle was attributed to the fresco: Sebastiano del Duro returned home from unjust imprisonment after his wife, Caterina, was advised by a visiting pilgrim to light a candle by the sanctuary.

[20] The sanctuary at Casale was heavily damaged during the Second World War:[20][23] German soldiers occupied the complex during the advance of the Gothic Line, and blew up the convent in their retreat on 23 September 1944.