In 1966, he was the first to illustrate one of Italy's most important adult comics, Isabella, written by Renzo Barbieri and Giorgio Cavedon.
He was also involved in the creation of Goldrake, Vartan, Una, Belzeba and La Poliziotta.
[1] Amongst the group of Italian artists who created comic strips for adults between the 1960s and 1970s, (which had become increasingly pornographic by the eighties), the style of Sandro Angiolini stands out.
Characters are drawn in a sometimes simplistic fashion with an emphasis on essential features and strong expressions to complement and move the narration forward.
A prolific artist, he has created illustrations for the most varied types of publication, and in periods of most intense activity was known, with the help of some colleagues, to produce two pocket books full of art in a month, amounting to 460 panels in two stories.