The Mouse Genetics Project (MGP) is a large-scale mutant mouse production and phenotyping programme aimed at identifying new model organisms of disease.
For each mutant line, groups of seven male and seven female mice move through a standard analysis pipeline aimed at detecting traits that differ from healthy C57BL/6 mice.
[1] The pipeline collects many measurements of viability, fertility, body weight, infection, hearing, morphology, haematology, behaviour, blood chemistry and immunity and compares them to wild type controls using a statistical mixed model.
[5] These data are immediately shared among the scientific and medical research community through a bespoke open access database,[6] and summaries are displayed in other online resources, including the Mouse Genome Informatics database and the Wikipedia-based Gene Wiki.
[4] As of July 2013, the MGP reports having over 900 mutant lines openly available to the international research community,[4] and have "substantively complete" analysis for over 650 mutant lines,[6] of which over 75 per cent have at least one abnormal phenotype.