Sant'Adriano III Papa is a Roman Catholic parish church located in Spilamberto, province of Modena, region of Emilia-Romagna, Italy.
A church was founded at the site in the 13th century by the Abbot of Nonantola and dedicated to Pope Adrian III, who died in 885 nearby.
The interior houses a terracotta Madonna della Rondine by Michele da Firenze and an anonymously sculpted Beata Vergine degli Angioli.
There are two terracotta Depositions: a 19th-century work by Giuseppe Obici in the sacristy and another by Prudenzio Piccioli.
Among the painters are Ippolito Scarsella, Jacopo Zoboli, F. Madonnina, Francesco Stringa, and R. Franciosino.