In the Lombard period the town had reached a considerable size and was part of the Duchy of Spoleto, more precisely in the Gastaldato di Ponte.

[4] In the seventh century the convent Santa Maria delle Rose was built by the Benedictines and shortly afterwards the town passed under the control of the abbey of Farfa.

In the mid-fourteenth century, following the attempt of Cardinal Albornoz to reduce the castles of the Marca under the dominion of the Pope, Sant'Angelo underwent the siege and conquest by the papal troops.

However, damage was soon repaired and Sant'Angelo returned to be part of the territory of Fermo, following its the fate until the Napoleonic period when it was included in the Department of Tronto.

[7] The first part of the name is a reference to Saint Michael Archangel, worshipped by the Lombards, whose image appears on the village coat of arms on a bridge (recalling the Italian word ponte, from the Latin pons, pontis); according to popular tradition, the last word derives from pantano meaning swamp or marsh, as it seems that in early times there was some marshland in the valley below the village.

In the hamlet of Passo Sant'Angelo, on the route of the Fiastra valley there is a PIP area where some small industrial and logistic activities take place.