The ancient Roman city of Tifernum Mataurense which lies underneath Sant'Angelo in Vado became a municipium at the beginning of the 1st century BC.

The city was built on a grid with the main cardo maximus running past the public baths and terminating at a forum which lies beneath the former convent of Saint Catherine.

Among the themes depicted are particularly: Neptune and Amphitrite on the triumphal chariot pulled by sea horses followed by Dionysus, god of wine and then arriving at the petrifying face of Medusa.

Another spectacular room is the triclinium in which a hunting and fishing scene are depicted surrounded by a festive repertoire of black and white geometric motifs.

From there the visitor would pass over a sandstone threshold and along a corridor with a mosaic floor depicting four two-tone geometric squares except for a pink floral element (room 20).

The town is represented by Vadese Calcio [it], an amateur football (soccer) club founded in 1952, mainly competing in Eccellenza, Promozione and Serie D. Its colors are yellow and red.