Santa Anna is a census-designated place (CDP) in Starr County, Texas, United States.

This was a new CDP for the 2010 census, with a population of 13.

[1] Santa Anna is located at 26°40′9″N 98°33′28″W / 26.66917°N 98.55778°W / 26.66917; -98.55778 (26.669238, -98.557884).

[2] Santa Anna first appeared as a census designated place in the 2010 U.S.

[15] The CDP is within the San Isidro Independent School District.