Santa Croce e San Bonaventura alla Pilotta or Santa Croce e di San Bonaventura dei Lucchesi is a church in Rome, sited on via dei Lucchesi in the Trevi district, between the Trevi Fountain and the Pontificia Università Gregoriana.

They moved to a new monastery on Piazza Barberini in 1631 and the church was granted to the Luccans by pope Urban VIII.

There was already a small Luccan community in Rome, mainly made up of merchants.

They demolished the old church in 1685 and built a new one in 1695 to designs by Mattia de Rossi and dedicated to the Most Holy Cross (Santissima Croce), after the cult of the 'Volto Santo', a piece of the True Cross venerated in Lucca Cathedral.

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