The village was formed as a result of the combined efforts of the people who lived in what was called “Old Santa Cruz“, Banana farm workers and Fisherman of the area.

“Old Santa Cruz” was made up of a few houses situated about 2 miles north of the Placencia junction on the Southern Highway, it was demolished for the extension of a banana plantation in the year 2005 by a local developer.

What is now Santa Cruz Village, was first settled by various ethnic groups which includes Mestizo, Maya, and Belizean Creole.

The origin of the name dates back to the beginning of this New century at the time the village was established.

Many residents of Santa Cruz Village commute for work daily to the nearby Banana Farms (Belize's productive agricultural heartland), Shrimp Farm Factory and also to the popular "The Placencia Peninsula” as it is home to significant tourist destination.