Santa Isabel has municipal boundaries with Rubiataba, Itapaci, Nova Glória, Rialma, and Carmo do Rio Verde.

Access from Goiânia is made by GO-080 / Nerópolis / São Francisco de Goiás / BR-153 / Jaraguá / Rianápolis / Rialma / GO-480.

The economy is based on modest agriculture, cattle raising, services, public administration, and small transformation industries.

The cattle herd had 74,000 head while the main crops were rice, sugarcane, beans, manioc, corn (800 hectares), and soybeans.

The infant mortality rate was 26.34 (2000) (the national average was 33.0) Human Development Index: 0.720 For the complete list see frigoletto.com.br