Santa Maria di Valvedre is a baroque-style, Roman Catholic parish church located on Via Squarcialupo #2 in the quarter of Castellamare of the city of Palermo, region of Sicily, Italy.

In 1633 it was refurbished funded by the endowment by a wealthy Genoese, Camillo Pallavicino, whose daughter had entered the monastery.

Initially, rebuilt under the designs of Mariano Smiriglio; work in the interior continued under Paolo Amato.

Additional work on the structure was concluded by Andrea Palma, Abate Mango, and finally in the 19th century by Giuseppe Patricolo.

The sottocoro, or entrance room underneath the second floor choir, was painted with a Virgin in Glory (1750) by Olivio Sozzi.