A monastery, and church, under the discalced Carmelite nuns under the rule of Saint Teresa of Avila were patronized in the first quarter of the 17th century by the then Duke of Montalto and his wife, Donna Maria, Princess of Paceco.
Received by the Princess of Paceco and the Cardinal Archbishop Francesco la Ribba, they were disembarked and installed in their cloistered setting.
In this, it recalls the facade of a church, four blocks north and also on Via Terramuzzo: Santa Maria della Pietà, also designed by the same architect Amato.
Inside, the first chapel or altar on the right, has an altarpiece depicting the Trasverberation of the Heart of St Teresa by Guglielmo Borremans.
The second chapel on the left, dedicated to the Madonna of the Carmine, has a painting depicting St John of the Cross by Sebastiano Conca.
In the register above the statues are four paintings related to the Eucharist, including The Widow of Zareptha brings Elijah bread; the Harvest of grapes; the Blessed Ruth gathers wheat in the fields of Boaz; and the Profanation of the sacrifice.