Sardis is a town in Panola County, Mississippi, United States.

According to the United States Census Bureau, the town has a total area of 2.0 square miles (5.2 km2), all land.

As of the 2020 United States Census, there were 1,748 people, 776 households, and 493 families residing in the town.

33.4% of all households were made up of individuals, and 18.6% had someone living alone who was 65 years of age or older.

The Town of Sardis is served by the North Panola School District.