Sastre is a town (comuna) in the west of the province of Santa Fe, Argentina, 139 km west from the provincial capital.

It had about 5,500 inhabitants at the 2001 census [INDEC] and it is the head town of the San Martín Department.

It is named after Marcos Sastre, a renowned Argentine lawyer, writer, and educator.

Miguel Brascó, the noted Argentine writer and food critic, hails from Sastre.

This article about a place in Santa Fe Province, Argentina is a stub.