Born in Thessaloniki, Greece, he can play both the power forward and the center positions.
[1] Manousos began his professional career in 2005 with KAOD in the Greek 2nd Division.
The same year, he joined Panevėžys of the Lithuanian Basketball League, where he stayed until the end of the season.
[2] In 2010, he moved to Anagenisi Flogas at Thessaloniki before leaving Greece in order to sign with the Slovak club BK NH Ostrava.
On January 5, 2017, Manousos left Kavala due to financial problems and signed with CB L'Hospitalet of Spain for the rest of the 2016–17 season.