First Hellenic Republic Ottoman Empire 1822–1824 Greek civil wars of 1824–1825 Egyptian intervention (1825–1826) Great powers intervention (1827–1829) The Second Siege of Missolonghi was the second attempt by Ottoman forces to capture the strategically located port town of Missolonghi during the third year of the Greek War of Independence (1823).

After the first unsuccessful attempt to take the town in 1822, another expedition to western Central Greece was undertaken, this time by Mustafa Pasha of Scutari.

[3] Meanwhile rumors arrived that the Ottoman campaign in Eastern Central Greece had failed and damaged the morale of those laying siege.

As a result of food shortages and disease, on 20 November Mustafa Pasha lifted the siege, withdrew and retreated to modern-day North Albania.

Its resistance achieved wider fame when Lord Byron arrived there, dying in the town of fever in April 1824.