A photographic reprint of the original edition was issued in both hardcover and trade paperback by Hyperion Press in 1974.

After a general introduction, individual chapters deal with particular authors, followed by a general survey of later or lesser writers (including C. S. Lewis, James Blish, Walter M. Miller, Jr., L. Ron Hubbard, Hal Clement, Ross Rocklynne, Poul Anderson, Cyril M. Kornbluth, Frederik Pohl, Alfred Bester, Edgar Pangborn, Kurt Vonnegut, Jr., Philip K. Dick, Ward Moore, John Hersey, John Christopher and Frank Herbert), an epilogue and an index.

Reviewing Seekers of Tomorrow, Algis Budrys noted that "Moskowitz is a master of denotation.

He added, however, that "Moskowitz knows and transmits, at least as much about the history of science fiction and its evolution, as anyone possibly could ... there is no other book like it".

[2] Kirkus Reviews called the work "a truly gratifying book ... [w]hat is satisfying is to see these authors deeply engaged in works of pure tripe and imagination (Barnum called it hokum) and watch them emerge with a fish so big (macrocosmic) that they become world-renowned.