Semqen (also Šamuqēnu) was a Hyksos ruler of Lower Egypt during the Second Intermediate Period in the mid-17th century BC.

[3][4] This opinion was shared by William C. Hayes and Wolfgang Helck but recently rejected by Kim Ryholt.

In his 1997 study of the Second Intermediate Period, Ryholt argues that the kings of the 16th Dynasty ruled an independent Theban realm c. 1650–1580 BC.

This analysis has convinced some Egyptologists, such as Darrell Baker and Janine Bourriau,[6][7] but not others including Stephen Quirke.

The original location of the seal, the title it is inscribed with and its design led Ryholt to propose that Semqen belonged to the early 15th Dynasty, although he also points to the conjectural nature of this proposition.