[2] Her father, Aman Khan Kheshgi was the first TV game show host on the state-run Pakistan Television.
In 1971, Senain was cast on the Children’s Television Workshop's groundbreaking show Sesame Street.
Early in her career, Kheshgi worked as a co-producer of the Peabody-winning film, "The First Year", directed by Davis Guggenheim.
Kheshgi then co-directed The Diplomat about the East German Olympic ice skater Katarina Witt with Jennifer Arnold for ESPN Films.
It is a window into Witt's life, who as one of the world's greatest ice skaters, still could not break free from Communist East Germany.