Senangkhanikhom (Thai: เสนางคนิคม, pronounced [sěː.nāːŋ.kʰá(ʔ).ní(ʔ).kʰōm]) is a district (amphoe) in the northern part of Amnat Charoen province, northeastern Thailand.

The minor district (king amphoe) was created on 15 December 1975, when the five tambons, Senangkhanikhom, Rai Si Suk, Phon Thong, Nong Hai, and Na Wiang were split off from Mueang Amnat Charoen district.

[2] In 1993 it was one of the districts split off from Ubon Ratchathani to form the new province, Amnat Charoen.

The district is divided into six sub-districts (tambons), which are further subdivided into 58 villages (mubans).

This Amnat Charoen Province location article is a stub.