Senigallia (or Sinigaglia in Old Italian; Romagnol: S'nigaja) is a comune (municipality) and port town on Italy's Adriatic coast.

[citation needed] In 284 BC, the area and the settlement were taken over by Romans, who established the colony Sena Gallica there to control the region they called the Ager Gallicus.

[citation needed] In the 15th century, Senigallia was captured and recaptured many times by opposing sides during the Guelph and Ghibelline war.

In 1516, this was temporarily revoked by Pope Leo X, who transferred the Lordship to his nephew Lorenzo II de' Medici, then again the Della Rovere family took over from 1624 when Senigallia eventually was annexed to the Papal States' legation (province) of Urbino.

During the First World War, the town and its port were devastated by intensive shelling by units of the Austro-Hungarian Navy led by the battleship SMS Zrínyi.

The municipality borders Belvedere Ostrense, Mondolfo (PU), Monte San Vito, Montemarciano, Morro d'Alba, Ostra and Trecastelli.