Serodino is a town (comuna) in the province of Santa Fe, Argentina.

The economy of the region is based on soybean, corn and wheat produce, and on cattle raising.

The town was founded on December 5, 1885, by Pedro Serodino, who sold the Central Argentino railway company the tract of land where the train station was raised, and built the first house in town (his own).

Serodino is the hometown of Argentine novelist Juan José Saer.

This article about a place in Santa Fe Province, Argentina is a stub.