Sesamin is a lignan isolated from the bark of Fagara plants and from sesame oil.

It has been used as a dietary fat-reduction supplement.

Its major metabolite is enterolactone, which has an elimination half life of less than 6 hours.

[1] Sesamin and sesamolin are minor components of sesame oil,[2] on average comprising only 0.14% of the oil by mass.

[3]