Sesamol is a natural organic compound which is a component of sesame seeds and sesame oil, with anti-inflammatory, antioxidant, antidepressant and neuroprotective properties.

Sesamol has been found to be an antioxidant that may prevent the spoilage of oils.

[2][3] It also may prevent the spoilage of oils by acting as an antifungal.

[5]: 138–141 Sesamol's molecular targets and mechanism of action, at least for its antidepressant-like effects, is found to be through the brain nerve growth factor (NGF) and endocannabinoid signalling under the regulatory drive of the CB1 receptors.

[6] Alexander Shulgin used sesamol in his book PiHKAL to make MMDA-2.