Sestri Ponente is an industrial suburb of Genoa in northwest Italy.

It is situated on the Ligurian Sea four miles to the west of the city, between Pegli[1] and Cornigliano.

The name is derived from the Latin Sextum, a small village that was likely founded in the second century A.D., where stones were assembled for the Roman road that left from Genoa.

Around 1911, the town had iron-works saw-mills, shipbuilding yards and tanneries and factories for macaroni, matches and tobacco.

[1] The links to the transport sector continue to this day; Sestri Ponente is home to Genoa Cristoforo Colombo Airport.