[9] At the time of the 2010 MLB draft, he had a 12–0 win–loss record, a 3.06 earned run average (ERA), 98 strikeouts and 22 walks in 97 innings pitched for the Sun Devils that season.
In April 2012, following pain experienced while throwing, Blair was diagnosed with an enchondroma, a benign tumor in a joint of his middle finger on his pitching hand.
[11] After the 2012 season, the Cardinals assigned him to the Surprise Saguaros of the Arizona Fall League, where he had a 2–1 record, a 2.25 ERA, 22 strikeouts, and 14 walks in 20 innings pitched.
Blair returned to baseball in 2019, signing a minor league contract with the San Diego Padres on May 24, 2019.
[16] On August 7, 2020, Blair signed a minor league contract with the Boston Red Sox and was added to their 60-man player pool.
[17] On December 22, 2020, Blair was re-signed by the Red Sox to a minor-league deal for the 2021 season,[18] and was selected as a non-roster invitee to major league spring training in 2021.
[19] Blair began the 2021 season in Triple-A with the Worcester Red Sox, and was reassigned to the Double-A Portland Sea Dogs in late May.
[22][23] Blair made 21 appearances for the Triple-A Durham Bulls, battling to an 0-3 record and a 7.61 ERA with 17 strikeouts in 23+2⁄3 innings pitched.