[4] In 2004, Kelkar made his television debut with the show Aakrosh which aired on Doordarshan in which he played the role of Inspector Sachin Kulkarni.

[5] His wife Keerti Gaekwad Kelkar is a television actress who has appeared in Saat Phere – Saloni Ka Safar as Chandni / Devika in a negative role.

In 2007, Kelkar hosted Rock-N-Roll Family along with former Hero Honda Sa Re Ga Ma Pa Challenge 2007 contestant Mauli Dave.

Then he appeared as Thakur Digvijay Singh Bhadoria in Bairi Piya which earned him critical acclaim for his performance.

[8] In 2012, he replaced Mohnish Behl as Dr. Ashutosh in the serial Kuch Toh Log Kahenge which aired on Sony Entertainment Television India.

[12] He describes his role as "Here's a guy who is suave and dapper, with an IQ that can give even the most intelligent and shrewd criminal a run for his money.

In 2017, Kelkarwas seen in Indian television show Koi Laut Ke Aaya Hai as Rishabh Singh Shekhari.

[16] He also acted in Sangharsh Yatra Biopic of late Gopinath Munde a famous BJP politician in Maharashtra.

Anna M. M. Vetticad of Firstpost praised the portrayal of Laxmii by Sharad Kelkar calling it a mature performance.

[21] He was also seen in ZEE5 series Black Widows opposite Mona Singh in December 2020 In 2021, Kelkar played the role of a military officer in the film Bhuj: The Pride of India.