The placental extract allegedly serves as a source of protein and hormones, predominantly estrogen and progesterone, in the cosmetics in which it is used.
The FDA maintains that placenta extract may be hazardous and its use is subject to restrictions and requirements of warnings in at least some products.
In case of chronic atrophic rhinitis placenta extract is injected to the nasal submucosa.
[4] Albert David Limited a Pharmaceutical company from India also manufactures an Injection from fresh human Placenta called Inj.Placentrex.
Hormone Replacement Therapy containing estrogen, while protective against osteoporosis, has been found to increase the risk of venous emboli and breast cancer.