It is in the central part of the city, in close proximity to many well-known landmarks, including the Shot Tower for which it is named, Port Discovery, Power Plant Live!, the Harbor campus of Baltimore City Community College, the National Aquarium, the Flag House, and Little Italy.

The Shot Tower station is one of two stops in the third phase of the Baltimore Metro, having opened in 1995.

In Season 2, Episode 1 of House of Cards, U.S. Rep. Frank Underwood (D-S.C.) meets with reporter Zoe Barnes at the fictitious Cathedral Heights Metro station.

The actual scene was filmed at Shot Tower station in Baltimore.

This article relating to rapid transit systems in the United States is a stub.