Sierra del Tigre is a mountain range in northeastern Sonora, Mexico at the northern region of the Sierra Madre Occidental.

The region contains sky island mountain ranges, called the Madrean Sky Islands, some separated from the Sierra Madre Occidental proper, and occurring in the northeastern Sonoran Desert, and extreme west-northwestern Chihuahuan Desert.

The range is southeast of Douglas, Arizona-Agua Prieta, Sonora.

The riparian protected wetland and grassland to the north in the San Bernardino Valley is the San Bernardino National Wildlife Refuge; Leslie Canyon National Wildlife Refuge is also nearby.

This article about a location in the Mexican state of Sonora is a stub.