Sigrid Hupach was born on 9 September 1968 in Leinefelde, where she attended the Geschwister Scholl Polytechnic Secondary School from 1975 to 1985.
From 1985 to 1987, she received training as a Facharbeiter für Schreibtechnik [de] - an officially recognized office management job of East Germany.
From 2012 to 2013 she was a constituency worker in Mühlhausen for then-member of the Thuringian state parliament Jörg Kubitzki [de] (the Left).
[1] In the 2013 German federal election, she was her Party's candidate in the Eichsfeld – Nordhausen – Unstrut-Hainich-Kreis I electoral district, where she received 26.091 (19.8%) votes, coming second after Manfred Grund of the Christian Democratic Union.
On 15 March 2024, her Party elected her one of the deputy leaders of the Thuringian state association along with Matthias Herzog, behind Katja Wolf and Steffen Schütz.