It was established on August 3, 1996, as Siloam Gleneagles Hospital that was a collaboration between Lippo Group and Gleneagles Hospital, founded through PT Sentralindo Wirasta which is engaged in health services.

[3] [4] Siloam is the first hospital in Indonesia to receive an accreditation by the Joint Commission International (JCI) from the United States.

Building on its reputation for excellence, Siloam has achieved several significant medical milestones.

Siloam ASRI successfully performed its 100th kidney transplant, demonstrating its expertise in advanced medical procedures.

Siloam Hospitals Group also operates Mochtar Riady Institute of Nanotechnology (MRIN) and the Pelita Harapan University School of Medicine and School of Nursing.