[4] He completed his secondary education in Arad, Romania, continuing his theological studies in Sibiu and later in Athens, Greece.

In 2002, Mănuilă was named hegumen of the skete Adormirea Maicii Domnului (Assumption of the Virgin Mary) in Körösszakál.

In 2003, he was appointed archimandrite and received the patriarchal cross, and until 2007, he was the cultural assessor of the Diocese of Gyula.

[2] On 4 August 2014, the President of Romania Traian Băsescu awarded him and many other bishops the Order of Cultural Merit for their efforts in getting involved in the lives of the Romanian diaspora in other countries (Hungary in Mănuilă's case).

[1] On 1 August 2017, Mănuilă also became leader of the Diocese of Dacia Felix in Serbia due to health problems of the previous bishop, Daniil Stoenescu.