Sir John Guise, 2nd Baronet

Sir John Guise, 2nd Baronet (c.1654 – November 1695) of Elmore Court, Gloucestershire was an English landowner and Member of Parliament.

He returned in 1688 with William of Orange and then took part in the capture of Bristol as Colonel of a foot regiment.

Re-elected for Gloucestershire to the Convention Parliament of 1689 he was an active member, serving on many committees.

He died of smallpox in November 1695 and was buried in St John the Baptist church, Elmore.

He had married, in 1674, Elizabeth, the daughter of John Grobham Howe of Little Compton, Withington, Gloucestershire, a previous MP for the county.