[citation needed] Their sponsored ministries include Valley Catholic School and Maryville Care.

[citation needed] In 1843 the Missionaries of the Precious Blood migrated from Germany to the United States, settling in Ohio.

As a result, Father Joseph Albrecht (along with a group of parishioners, Sisters, and Brothers), left the community.

[1][2] Archbishop William Hickley Gross visited the colony and laid out a plan for reconciliation with the Catholic Church.

[1][2] The group's elders rejected the plan, but the women asked to come along with the bishop, who wanted them to become a formal religious community.

[1] On March 25, 1887, five of the Sisters made their first Profession of Vows: Theresa Arnold, Emma Bleily, Cecilia Boedigheimer, Josephine Eifert, and Clara Hauck.

In 1889, Archbishop Gross approved construction of St. Mary's Orphanage in Beaverton, Oregon and asked the Sisters to staff it.

In January 1903, the Sisters opened a boarding school on their campus which served both boys and girls: St. Mary's Academy.

They opened a number of schools in Oregon, and in 1958 Mother Collete Lorch authorized the Sisters to begin teaching in Spokane, Washington.

In 1957, Sister Imelda Vandehey received the first of two papal recognitions, the Pope Pius X medal for her ministry in education.

The Sisters continued to extend the reach of the ministries when Mother Angela Lehman approved their first international mission.