[11] Beginning in 2006, Dunning hosted and produced Skeptoid, a weekly audio podcast dedicated "to furthering knowledge by blasting away the widespread pseudosciences that infect popular culture, and replacing them with way cooler reality".

Each episode is under four minutes long and covers issues similar to those explored in more depth in the Skeptoid podcast, but is intended to reach a wider audience due to its brevity and availability on YouTube.

[13] In 2008 Dunning produced Here Be Dragons, a free 40 minute video introduction to critical thinking intended for general audiences,[14] and received an award from the Portland Humanist Film Festival for this in November 2011.

[16] In August 2010 he received an award recognizing his contributions in the skeptical field from the Independent Investigations Group (IIG) during its 10th Anniversary Gala.

"[18][19] In October 2019, a special preview of the Skeptoid Media documentary, Science Friction, was shown after CSICon in Las Vegas.

[20] Dunning has written articles for Skepticblog.org, published by The Skeptics Society,[21] and was an executive producer for the unreleased network television pilot The Skeptologists.

[22] He is a member of the National Association of Science Writers,[23] and is the "Chancellor" of the non-accredited "Thunderwood College", a parody of unaccredited institutions of higher learning which offer "degrees" in a variety of subjects.

[25] On April 15, 2013, in the San Jose, California, U.S. District Court, as part of a plea agreement, Dunning pleaded guilty to wire fraud.

[27][28][29] In a statement on his website, Dunning explained the circumstances, and initially accepted responsibility for his actions,[28] although in a later account claimed to have been in the right and to have only pled guilty in order to protect his family and to avoid a longer jail term.

[35][36][37][38][39][40] Despite his shift away from the technology industry, Dunning continues to do computer programming, and does web development for his Skeptoid website.

It was released on Amazon Prime Video in 2022 and starred Matt Kirshen, Janine Kippner, Simon Singh, Banachek, Steven Novella, Michael Shermer, Richard Dawkins, Ben Radford, Zubin Damania, and Ken Feder amongst other scientists.