After working for a time in a notary, he went to Geneva (Switzerland) to study law, but became here part of the anarchist "Geneve group", founded in 1898 by Petar Mandjukov and closely related to the Internal Macedonian-Adrianople Revolutionary Organization (IMARO).
Following his decision to devote himself to the struggle for the liberation of Macedonia and Thrace from Ottoman rule, he went in 1899 to Skopje where, after some time, he was arrested by the authorities and thrown in prison.
The first meetings of the group took part with the purpose of forming a revolutionary circle with aim of changing international public opinion in the matter of the freedom of Macedonia and Adrianople Thrace.
[3] Subsequently, in 1899, Merdzhanov with Mandjukov and Petar Sokolov, was part of the guerrilla group of Gotse Delchev, and become a member of the IMARO.
In 1900 he arrived in Istanbul where Merdzanov created the anarcho-terrorist group and with Pavel Shatev, Mandjukov and Sokolov participated in the preparation of blasting of the Ottoman Imperial Bank's central office, for which they dig a tunnel.
One of which was to hold up the Orient Express on Turkish territory near Adrianople, and to gain possession of the mail in order to finance future actions.