The film stars Noah Segan, Andrea Rueda, Ezra Buzzington, Jon Budinoff, Silvia Spross, Elina Madison, Ricardo Gray, Lew Temple, Vernon Wells, and Timothy Muskatell.

The film follows a group of drug-addled medical school students, Justin, Meg, Sebastian, and Joe, who are targeted by John and Wilma Hopper, a married sexually sadistic serial killer couple from the 1970s who rape their victims to death.

Ray Harris (Jordan Lawson), a med student, sits in his dorm, watching stag films and shooting what at first appears to be heroin but is later revealed to be an experimental drug called "Taldon".

A flashback shows the six friends using Taldon, the drug found at the scene of Ray's murder, and reading the case files of John and Wilma Hopper, a serial killer couple that was the subject of an intensive study at the school when it was still a mental hospital.

Everything that has happened is revealed to be Justin's dying hallucination; he and his friends had overdosed on Taldon the night they first read about the Hopper spree.

[8] Bloody Disgusting rated it 2.5/5 stars and wrote that "there is a meaning behind it all", but "the third act feels a little cheap and on-the-nose, at odds with the deceptively off-the-cuff invention that brings us to that point".

[9] Steve Barton of Dread Central rated it 4/5 stars and called it "a love letter" to transgressive 1970s grindhouse cinema.

[12] Stephanie Scaife of Brutal as Hell wrote, "It's not absolutely dreadful and it is pretty much no-holds-barred in its approach to the rather outlandish subject matter.