She primarily writes and draws characters who are adolescent or young adult women, including various races, body types, sexual orientations, and abilities.
In 2019, she became the lead writer of IDW's Teenage Mutant Ninja Turtles, for which she designed the character Jennika.
[2][3] Campbell is the creator of several graphic novels, including The Abandoned,[4] Mountain Girl, Shadoweyes, Wet Moon, and Water Baby.
In 2008, she drew the story "The Hollows" for the first issue of the DC/Vertigo comic House of Mystery written by Bill Willingham.
She drew issues of Teenage Mutant Ninja Turtles for IDW, and in March 2015 she became the artist for their new Jem and the Holograms series written by Kelly Thompson.