They are most commonly known as plant pigments in flower petals to attract pollinators and for their antioxidant activities, providing some hope for consumers regarding medicinal uses, potentially cancer treatment.

No known toxicity reports against humans have been found related to phytoncides, including sophoraflavanone G. In result to the increasing cases of MRSA and VRE, a tremendous amount of research has gone into finding reliable methods of controlling and potentially preventing antibiotic-resistant strains of bacteria.

Serious staph infections are more common in people with weak immune systems, particularly patients in hospitals and long-term healthcare facilities and those who are healthy, but otherwise in close contact with many individuals through shared use of equipment and personal items, like athletes and children in daycare.

When this compound is combined with vancomycin, minocycline, and rifampicin, the rates of inhibition increased, indicating a partially synergistic effect with anti-MRSA antibiotics.

[4] Similarly in Iran, in 2006, a research group reported that the antibacterial activity of gentamicin was enhanced through the use of sophoraflavanone G, citing that bacterial colonies of S. aureus, on TLC plates showed a significant decrease (4x) in growth while in the presence of small amounts (.03 μg/mL) of this compound.

Regarding anti-inflammatory treatments, sophoraflavanone G inhibits eicosanoid generating enzymes, and prostaglandin production, suggesting its potential use for eicosanoid-related skin inflammation such as atopic dermatitis.

[8] In 2004, Youn et al. reported that sophoraflavanone G (in addition to other flavanoids) showed moderate anti-malarial activities based on the EC50 values within mice populations, potentially due to methoxyl groups found within the structure.