South Carolina Highway 114 (SC 114) is a 6.360-mile-long (10.235 km) state highway in the U.S. state of South Carolina.

The highway travels through rural areas of Union County.

The highway has both termini at SC 18 and passes to the east of Jonesville.

It travels to the north-northeast to an intersection with SC 9 (Jonesville–Lockhart Highway).

The highway curves to the northwest, crosses over Sandy Run Creek, and meets its northern terminus, another intersection with SC 18.