SC 200 is mostly a rural two-lane highway, traversing northwest from Winnsboro, through Great Falls and Lancaster, to the North Carolina state line.

[6] Established in 1938 as a renumbering part of SC 93 to match NC 200; it originally traversed 7 miles (11 km) from US 521 to the North Carolina state line.

[7] South Carolina Highway 93 Alternate (SC 93 Alt.)

South Carolina Highway 200 Connector (SC 200 Conn.) is a 0.490-mile-long (0.789 km) connector route that is completely within the north-central part of Winnsboro and the central part of Fairfield County.

It bends slightly to the west-northwest just before it reaches its northern terminus, an intersection with the SC 200 mainline.