The highway travels through eastern Columbia, and connects the main part of the city with Fort Jackson.

SC 760 begins at an intersection with U.S. Route 76 (US 76) and US 378 (Devine Street) and the eastern terminus of the central segment of unsigned US 76 Conn. (Cross Hill Road) in Columbia, Richland County.

This intersection is just northeast of Midlands Technical College's Beltline Campus.

It then meets an interchange with Interstate 77 (I-77; William Earle Berne Beltway).

A short distance later, it reaches its eastern terminus, a crossing over Wildcat Creek.