The highway connects rural areas of Marion County with Brittons Neck.

SC 908 begins at a skewed intersection with U.S. Route 378 (US 378) northeast of Johnsonville, Marion County, where the roadway continues south as a dirt road to the Woodbury Wildlife Management Area.

It travels to the north-northwest and curves to a nearly due north direction.

Just before it travels through Brittons Neck, it curves to the north-northwest and crosses Alligator Run.

Just after crossing Marsh Creek, it meets its northern terminus, an intersection with SC 41 at a point south of Centenary.