South Portland High School is a public high school located in South Portland, Maine, United States.

The first high school in what is now South Portland was built in 1874 while the City was part of Cape Elizabeth, Maine.

The current building on Highland Avenue was erected in 1952, with a gymnasium added in 1958, an annex in 1962, and an auditorium and cafeteria in 1997.

[3] The current high school building has been renovated and expanded.

The first stage of expansion to the school was complete in early January 2014.