Southpoint is a commercial section of Jacksonville, Florida on the city's Southside area, eight miles from Downtown.

The area is composed primarily of commercial buildings, apartment complexes and professional office centers.

Some businesses between I-95 and Philips Highway use Southpoint to reference their location, and there are many small hotels on that strip of land.

Many of the hospital's doctors have offices in Southpoint and employees live in nearby apartments.

The population is 8,078, primarily young professionals and families who rent and are political moderates.